New PDF release: Advancements of Mass Spectrometry in Biomedical Research

By Alisa G. Woods, Costel C. Darie

ISBN-10: 3319060678

ISBN-13: 9783319060675

ISBN-10: 3319060686

ISBN-13: 9783319060682

This quantity explores using mass spectrometry for biomedical purposes. Chapters concentrate on particular healing components comparable to oncology, infectious disorder and psychiatry. extra chapters concentrate on method in addition to new applied sciences and instrumentation. This quantity presents readers with a entire and informative guide that would let them relish mass spectrometry and proteomic examine but in addition to start up and enhance their very own paintings. hence the ebook acts as a technical advisor but in addition a conceptual advisor to the latest details during this interesting field.

Mass spectrometry is the valuable software utilized in proteomic examine at the present time and is swiftly turning into integral to the biomedical scientist. With the crowning glory of the human genome undertaking and the genomic revolution, the proteomic revolution has heavily in the back of. realizing the human proteome has turn into severe to easy and scientific biomedical learn and holds the promise of offering accomplished realizing of human physiological strategies. moreover, proteomics and mass spectrometry are bringing extraordinary biomarker discovery and are aiding to customize medicine.

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Camacho-Carvajal MM, Wollscheid B, Aebersold R, Steimle V, Schamel WW (2004) Twodimensional Blue native/SDS gel electrophoresis of multi-protein complexes from whole cellular lysates: a proteomics approach. Mol Cell Proteomics 3:176–182 5. Gygi SP, Rist B, Gerber SA, Turecek F, Gelb MH, Aebersold R (1999) Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat Biotechnol 17:994–999 6. Ong SE, Foster LJ, Mann M (2003) Mass spectrometric-based approaches in quantitative proteomics.

J Proteome Res 5:581–588 9. Darie C (2013) Mass spectrometry and proteomics: principle, workflow, challenges and perspectives. Mod Chem Appl 1:e105 10. Darie CC (2013) Mass spectrometry and its application in life sciences. Aust J Chem 66:1–2 11. Ngounou Wetie AG, Sokolowska I, Woods AG, Darie CC (2013) Identification of posttranslational modifications by mass spectrometry. Aust J Chem 66:734–748 12. Ngounou Wetie AG, Sokolowska I, Woods AG, Roy U, Deinhardt K, Darie CC (2014) Protein-protein interactions: switch from classical methods to proteomics and bioinformaticsbased approaches.

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Advancements of Mass Spectrometry in Biomedical Research by Alisa G. Woods, Costel C. Darie


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