By Mohammed Sarwar
ISBN-10: 1461296145
ISBN-13: 9781461296140
ISBN-10: 1461325714
ISBN-13: 9781461325710
Computed Tomography of Congenital mind Malformations
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Extra resources for Computed Tomography of Congenital Brain Malformations
Sample text
Lateral ventricles are undivided (nonventricle). ,. Figure 6. Pathologic specimen of a semilobar to lobar holoprosencephaly. Note monoventricle in the upper coronal brain section. The interhemispheric fissure is present. There is macrogyria. The choroid plexi are unusually prominent. F. ] 55 Holoprosencephaly (Prosencephaly) PRECHORDAL MESODERM SCHEMATIC LO NGI TUDIN AL SECTION OF 21=DAY EMBRYO PRIMARY DEFECT IN PRECHORDAL MESODERM Pr ior 10 21 - 25 doys 2B days Single ventricle Absence of / corpus callosum Fused tha lam i Incompl ete anterior and posterior pi tu i tory INCOMPLETE CLEAVAGE AND MORPHOGENESIS OF FOREBRAIN ~I l Icrocepholy Seve re mental defect Apneic episodes Sei zures Abnormal EEG Infant death MISSING OR INCOMPLETE MIDFACIAL DEVELO PM ENT Hypotelonsm Absent philtrum Absent nasal septum Single nar i s Probosc is Lock of e~ ~ mOld bone Cyclopia Anophthalmia Mlc rophtho Imio Colo boma, iris Retinol defect Lac of olfoctory tobes Lock of op l lc nerve Figure 7.
17. Singer WD, Haller JS, Sullivan LR et al: The value of neuroradiology in infantile spasms. J Pediatrics 100:47-50, 1982. 18. Byrd SE, Harwood·Nash DC, FitzCR: Absence of the corpus callosum: computed tomographic evaluation in infants and children. J Can Assoc Radiol 29:108-112, 1978. 19. Guibert-Tranier F, Piton J, Billerey J, Caille JM: Agenesis of the corpus callosum. J Neuroradiology 9:135·160,1982. 20. Fitz CR: Midline anomalies of the brain and spine. Rad Clin N Amer 20:95-104,1982. 4 Holoprosencephaly (Prosencephal y) HISTORY, DEFINITION AND GROSS MORPHOLOGY (1-5) Initially described by Rudius in 1588 (4), holoprosencephaly comprises malformation of the brain and the face.
B. Skull films. Midline bony structures are absent (arrow), and there is hypotelorism with absence of crista galli. The skull is microcephalic. Absence of sella turcia indicates concomitant pituitary aplasia.
Computed Tomography of Congenital Brain Malformations by Mohammed Sarwar
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